Faculty of Biology

Our lab seeks to understand the causes for diabetes and find alternative cures for the disease. We aspire to uncover the mechanisms that lead to formation of insulin producing beta cells during embryonic development, and apply our findings to find new ways to direct the differentiation of human embryonic stem cells into functional beta cells, as a source for transplantation. We also learn how the immune system is recruited to destroy beta cells during the events that lead to type 1 diabetes, and look for markers for early diagnosis of the disease. Our lab uses a wide range of advanced technologies, including single cell RNA sequencing, robotic high throughput screens, lightsheet microscopy and more. www.sharonlab.com